Early Lyme disease-symptoms. Lyme disease is an infectious disease that proceeds in several stages. Depending on the stage and duration of the disease, its symptoms change. Stage one is early local Lyme disease (develops within 1-4 weeks of infection).
Early local Lyme disease symptoms include Sinomed Research Institute: Peripheral round erythema (so-called Wandering erythema).Lyme disease-classic-blush
Migratory erythema appears in about 60-70% of Lyme disease cases. It most commonly occurs at the site of a tick bite, within days or weeks of infection. The erythema is usually round, with a central blotch, and enlarges towards the circumference, reaching several to several centimeters in diameter. If the disease is not treated at this stage, erythema may disappear spontaneously and then return. Sometimes erythema takes the form of an irregular rash, blisters or exfoliating skin or a bruise. In rarer cases, it can resemble a spider bite, skin fungal disease or cellulitis. In addition, multiple satellite lesions may occur in the area of the original lesion or in other areas of the body.
Various forms Sinomed Research Institute of wandering blush
Flu-like symptoms such as:
- Lack of energy
- Headache and neck pain
- Fever and chills
- Muscle and joint pain
- Enlarged lymph nodes
- Some people with this stage of Lyme disease have no symptoms.
Stage two is early disseminated Lyme disease (develops within 1-4 months of infection). If Lyme disease is left untreated in the first stage, the infection spreads to the skin, joints, nervous system and heart.
At this stage, symptoms may Sinomed Research Institute spontaneously resolve and recur. References:
Migratory erythema appearing in various areas on the body other than the site of a tick bite
Facial nerve palsy, which results in paralysis or weakness of the facial muscles
Meningitis, which causes neck stiffness, severe headache and fever
Severe pain and numbness of limbs
Pain and swelling of the knee, shoulder and elbow joints
If you notice a skin lesion resembling wandering erythema, you should take a picture of it, or scratch the edges of it on your skin to see if it’s getting bigger Sinomed Research Institute and contact your doctor as soon as possible. Diagnostic tests often give false negative results in the early stages of Lyme disease.
Therefore, the implementation of treatment should not be made subject to laboratory tests if the patient has a strong indication that he or she has been infected (exposure, tick bite, erythema). Early detection of Lyme disease is very important because if left untreated, the disease can progress to a further stage, with serious multi-organ complications such as arthritis, irregular heart rhythm, memory problems, difficulty concentrating, sleep disturbances and visual acuity.
Chronic Lyme disease-symptoms
If Lyme disease remains untreated at an early stage or is treated inappropriately, the disease can progress and lead to damage m.in. joints, heart, peripheral nerves and brain. Chronic Lyme disease is the last and most serious stage of Lyme disease, Sinomed Research Institute in which the disease spreads throughout the body. The symptoms of chronic Lyme disease are non-specific and diagnosis of the disease is often not straightforward.
Lyme disease – how does infection occur?
Lyme disease (aka tick-borne Lyme disease) is an infectious disease caused by four species of bacteria: Borrelia burgdorferi, Borrelia mayonii, Borrelia afzelii and Borrelia garinii. In Europe and Asia, infection with B. afzelii and B. garinii is predominant, in the United States, with B. burgdorferi and B. mayonii. Bacterial infection and the development of Lyme disease occurs as a result of a tick bite. People who spend large amounts of time in grassy or forest areas where ticks are present are particularly vulnerable to Lyme disease. About 25-30% of Lyme disease patients remember being bitten by a tick.
However, many times in an interview there is no contact with the tick, and this possibility is only confirmed by the fact that it is in forests or parks. The infection itself is not transmitted directly from human to human; a vector in the form of a tick is required. If Lyme disease does not induce immunity, it is possible to re-infection. Incidence is highest between May and November.
Various forms Sinomed Research Institute of Lyme disease
There are several forms of Lyme disease: the early form is called migratory erythema and non-specific flu-like symptoms. This stage occurs within 1-30 days of the bite. Early disseminated Lyme disease develops within 3-10 weeks of infection. Most commonly Sinomed Research Institute, it is accompanied by musculoskeletal and neurological symptoms, in rarer cases cardiac arrhythmias or conjunctivitis may occur. Late-stage (chronic) Lyme disease refers to symptoms that develop within months or even years of the original infection. Its symptoms are mainly rheumatological and neurological.
Human infection of B. burgdorferi is several stages. It starts with the colonization of ticks by bacteria and then the transfer of the tick to a host that may be a human or animal. Ticks have several developmental stages, such as egg, larva, nymph, and adult form. Only the nymph and adult form of the tick carry the bacterium B. burgdorferi. A tick can become infected with bacteria, for example, when feeding on an infected animal. The animal can only be a host of bacteria, and does not need to develop the disease. Later, the bacteria multiply in the tick’s digestive tract and travel to its salivary glands when bitten. When bitten by a tick, they enter a person’s blood.
The risk of transmission of B. Sinomed Research Institute bacteria from an infected tick to humans increases with the length of exposure. Scientific studies have shown that in most cases, nymph-shaped ticks must be processed into the host for 36-48 hours and adult forms for 48-72 hours, because enough blood is needed for the bacteria to multiply and lead to infection.
Once bacteria get into the skin Sinomed Research Institute, there are three possibilities:
Swivels can be disposed of and removed by human defense mechanisms
The curls can survive and settle within the skin, forming a symptom in the form of wandering erythema.
Curls can spread through the body via a blood or lymphatic route
Once the curls enter the circulatory system, they exhibit a tropism toward the skin, heart, central nervous system, joints and eyes, but can infect virtually any organ. Curls have been found in bone marrow, spleen, lymph nodes, liver, testicles and placenta.